Comparative Cardiovascular Toxicity in Dogs Given Inotropic Agents by Continuous Intravenous Infusion
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چکیده
منابع مشابه
Volume kinetics of glucose solutions given by intravenous infusion.
Glucose solutions given by intravenous (i.v.) infusion exert volume effects that are governed by the amount of fluid administered and also by the metabolism of the glucose. To understand better how the body handles glucose solutions, two volume kinetic models were developed in which consideration was given to the osmotic fluid shifts that accompany the metabolism of glucose. These models were f...
متن کامل[Continuous intravenous glucose infusion tests].
Sixty minutes' intravenous glucose infusion tests were carried out in normal subjects, borderline cases, and diabetics which were diagnosed by 50 g oral glucose tolerance test . Infusion was performed at the rate of 5 mg/kg/min . or 15 mg/kg/min. using 5% or 10% glucose. The difference in the insulin responses among thesegroups was rather marked in the case of 15 mg/kg/min. infusion of 10% gluc...
متن کاملA phase I study of antisense oligonucleotide GTI-2040 given by continuous intravenous infusion in patients with advanced solid tumors.
BACKGROUND This study of GTI-2040, a 20-mer phosphorothioate oligonucleotide complementary to the messenger ribonucleic acid (mRNA) of the R2 subunit of ribonucleotide reductase (RNR), was conducted to determine the dose-limiting toxicity (DLT) and maximum-tolerated dose (MTD) of the agent in patients with advanced solid tumors or lymphoma. Plasma pharmacokinetics of GTI-2040 and suppression of...
متن کامل[Vasopressin intravenous infusion causes dose dependent adverse cardiovascular effects in anesthetized dogs].
BACKGROUND Arginine vasopressin (AVP) has been broadly used in the management of vasodilatory shock. However, there are many concerns regarding its clinical use, especially in high doses, as it can be associated with adverse cardiovascular events. OBJECTIVE To investigate the cardiovascular effects of AVP in continuous IV infusion on hemodynamic parameters in dogs. METHODS Sixteen healthy m...
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The cardiovascular effects during 2 hours of anesthesia with either a continuous propofol infusion or isoflurane were compared in the same six healthy dogs. Dogs were randomly assigned to be anesthesized with either propofol (5 mg/kg, i.v. administered over 30 seconds, immediately followed by a propofol infusion beginning at 0.4 mg/kg/min), or isoflurane (2.0% end-tidal concentration). The prop...
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ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 1990
ISSN: 0192-6233,1533-1601
DOI: 10.1177/019262339001800205